Recombinant Mouse Drap1 Protein, Myc/DDK-tagged

• Cat.No.: Drap1-2657M
• Product Overview: Purified recombinant protein of mouse full-length Dr1 associated protein 1 (negative cofactor 2 alpha) (Drap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 22.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Drap1 Dr1 associated protein 1 (negative cofactor 2 alpha) [ Mus musculus (house mouse) ]
• Official Symbol: Drap1
• Synonyms: DRAP1; Dr1 associated protein 1 (negative cofactor 2 alpha); dr1-associated corepressor; NC2-alpha; dr1-associated protein 1; negative co-factor 2-alpha; 2310074H19Rik
• Gene ID: 66556
• mRNA Refseq: NM_024176
• Protein Refseq: NP_077138
• UniProt ID: Q9D6N5