Recombinant Mouse Ecd Protein, Myc/DDK-tagged
Cat.No. : | Ecd-2714M |
Product Overview : | Purified recombinant protein of mouse full-length ecdysoneless cell cycle regulator (Ecd), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 71.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Ecd ecdysoneless cell cycle regulator [ Mus musculus (house mouse) ] |
Official Symbol : | Ecd |
Synonyms : | ECD; ecdysoneless homolog (Drosophila); protein SGT1 homolog; suppressor of S. cerevisiae gcr2; Hsgt1; 5730461K03Rik |
Gene ID : | 70601 |
mRNA Refseq : | NM_027475 |
Protein Refseq : | NP_081751 |
UniProt ID : | Q9CS74 |
Products Types
◆ Recombinant Protein | ||
ECD-1197R | Recombinant Rhesus Macaque ECD Protein, His (Fc)-Avi-tagged | +Inquiry |
ECD-5095H | Recombinant Human ECD Protein, GST-tagged | +Inquiry |
ECD-929H | Recombinant Human ECD Protein, MYC/DDK-tagged | +Inquiry |
ECD-1317H | Recombinant Human ECD protein(Met1-Thr621), His&GST-tagged | +Inquiry |
ECD-2619M | Recombinant Mouse ECD Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ECD-001HCL | Recombinant Human ECD cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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