Recombinant Mouse Fasn protein, His/Myc-tagged

• Cat.No.: Fasn-596M
• Product Overview: Recombinant Mouse Fasn(2201-2504aa) fused with N-terminal His tag and C- terminal Myc tag was expressed in E. coli.

Specification

• Description: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
• Source: E. coli
• Species: Mouse
• Tag: His/Myc
• Form: Tris-based buffer,50% glycerol
• Protein length: 2201-2504aa
• Purity: >90% ( SDS-PAGE )
• Storage: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade. Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.

Gene Information

• Gene Name: Fasn fatty acid synthase [ Mus musculus ]
• Official Symbol: Fasn
• Synonyms: FASN; fatty acid synthase; FAS; A630082H08Rik
• Gene ID: 14104
• mRNA Refseq: NM_007988
• Protein Refseq: NP_032014
• UniProt ID: P19096
• Chromosome Location: 11 E2; 11 84.56 cM
• Pathway: ChREBP activates metabolic gene expression, organism-specific biosystem; Fatty Acid Biosynthesis, organism-specific biosystem; Fatty Acyl-CoA Biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, conserved biosystem; Fatty acid biosynthesis, elongation, organism-specific biosystem; Fatty acid biosynthesis, elongation, conserved biosystem;
• Function: 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-