Recombinant Mouse Fgb protein, His-tagged

• Cat.No.: Fgb-5819M
• Product Overview: Recombinant Mouse Fgb aa. (Gly35~Gln481 (Accession # Q8K0E8)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: This gene encodes the beta subunit of the coagulation factor fibrinogen, which is a component of the blood clot. The encoded preproprotein is proteolytically processed by thrombin to release an N-terminal fibrinopeptide during the conversion of fibrinogen to insoluble fibrin polymer. The encoded protein interacts with the amyloid beta peptide to form fibrin clots of abnormal structure, and may play an important role in Alzheimer's disease. This gene is located adjacent to the genes encoding fibrinogen alpha and gamma subunits on chromosome 3.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 52.3kDa
• Protein length: Gly35~Gln481 (Accession # Q8K0E8)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 8.2.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Fgb fibrinogen beta chain [ Mus musculus (house mouse) ]
• Official Symbol: Fgb
• Synonyms: 2510049G14Rik; fibrinogen, B beta polypeptide; fibrinogen beta chain
• Gene ID: 110135
• mRNA Refseq: NM_181849.3
• Protein Refseq: NP_862897.1
• UniProt ID: Q8K0E8