Recombinant Mouse Flrt2 Protein, Myc/DDK-tagged

• Cat.No.: Flrt2-3042M
• Product Overview: Purified recombinant protein of mouse full-length fibronectin leucine rich transmembrane protein 2 (Flrt2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 74.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Flrt2 fibronectin leucine rich transmembrane protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Flrt2
• Synonyms: FLRT2; fibronectin leucine rich transmembrane protein 2; KIAA0405
• Gene ID: 399558
• mRNA Refseq: NM_201518
• Protein Refseq: NP_958926
• UniProt ID: Q8BLU0