Recombinant Mouse Flrt3 Protein, Myc/DDK-tagged Flrt3-3043M

Recombinant Mouse Flrt3 Protein, Myc/DDK-tagged

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Cat.No. : Flrt3-3043M Optional Service: Optional requirements on this protein
Product Overview : Purified recombinant protein of mouse full-length fibronectin leucine rich transmembrane protein 3 (Flrt3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina. Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members. Promotes neurite outgrowth (in vitro). Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length. Plays a role in the regulation of the density of glutamaergic synapses. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning. Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development. Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 72.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Flrt3 fibronectin leucine rich transmembrane protein 3 [ Mus musculus (house mouse) ]
Official Symbol : Flrt3
Synonyms : FLRT3; fibronectin leucine rich transmembrane protein 3; mKIAA1469; 5530600M07Rik; C430047I10Rik
Gene ID : 71436
mRNA Refseq : NM_001172160
Protein Refseq : NP_001165631
UniProt ID : Q8BGT1
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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