Recombinant Mouse Frmd8 Protein, Myc/DDK-tagged
Cat.No. : | Frmd8-3085M |
Product Overview : | Purified recombinant protein of mouse full-length FERM domain containing 8 (Frmd8), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway. By acting on iRhoms, involved in ADAM17-mediated shedding of TNF, amphiregulin/AREG, HBEGF and TGFA from the cell surface. Negatively regulates Wnt signaling, possibly by antagonizing the recruitment of AXIN1 to LRP6. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 51.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Frmd8 FERM domain containing 8 [ Mus musculus (house mouse) ] |
Official Symbol : | Frmd8 |
Synonyms : | FRMD8; FERM domain containing 8; FERM domain-containing protein 8; AU018809; 1200004M23Rik; 2310035N23Rik; 4931429L16Rik |
Gene ID : | 67457 |
mRNA Refseq : | NM_026169 |
Protein Refseq : | NP_080445 |
UniProt ID : | Q3UFK8 |
Products Types
◆ Recombinant Protein | ||
FRMD8-3363M | Recombinant Mouse FRMD8 Protein, His (Fc)-Avi-tagged | +Inquiry |
FRMD8-2049R | Recombinant Rat FRMD8 Protein, His (Fc)-Avi-tagged | +Inquiry |
FRMD8-1574R | Recombinant Rhesus Macaque FRMD8 Protein, His (Fc)-Avi-tagged | +Inquiry |
FRMD8-4205H | Recombinant Human FRMD8 Protein, GST-tagged | +Inquiry |
FRMD8-27032TH | Recombinant Human FRMD8, His-tagged | +Inquiry |
◆ Lysates | ||
FRMD8-6136HCL | Recombinant Human FRMD8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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