Recombinant Mouse Fstl3 Protein, Myc/DDK-tagged

• Cat.No.: Fstl3-3094M
• Product Overview: Purified recombinant protein of mouse full-length follistatin-like 3 (Fstl3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiation. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. The nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 27.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fstl3 follistatin-like 3 [ Mus musculus (house mouse) ]
• Official Symbol: Fstl3
• Synonyms: FSTL3; follistatin-like 3; follistatin-related protein 3; follistatin-like protein 3; follistatin-related gene protein; Flrg; E030038F23Rik
• Gene ID: 83554
• mRNA Refseq: NM_031380
• Protein Refseq: NP_113557
• UniProt ID: Q9EQC7