Recombinant Mouse GFAP protein(1-430aa), His&Myc-tagged

• Cat.No.: GFAP-1832M
• Product Overview: Recombinant Mouse GFAP protein(P03995)(1-430aa), fused with N-terminal His tag and C-terminal Myc tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Mouse
• Tag: N-His&C-Myc
• Protein length: 1-430aa
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 57.3 kDa
• AASequence: MERRRITSARRSYASETVVRGLGPS RQLGTMPRFSLSRMTPPLPARVDFS LAGALNAGFKETRASERAEMMELND RFASYIEKVRFLEQQNKALAAELNQ LRAKEPTKLADVYQAELRELRLRLD QLTANSARLEVERDNFAQDLGTLRQ KLQDETNLRLEAENNLAAYRQEADE ATLARVDLERKVESLEEEIQFLRKI YEEEVRELREQLAQQQVHVEMDVAK PDLTAALREIRTQYEAVATSNMQET EEWYRSKFADLTDAASRNAELLRQA KHEANDYRRQLQALTCDLESLRGTN ESLERQMREQEERHARESASYQEAL ARLEEEGQSLKEEMARHLQEYQDLL NVKLALDIEIATYRKLLEGEENRIT IPVQTFSNLQIRETSLDTKSVSEGH LKRNIVVKTVEMRDGEVIKDSKQEH KDVVM
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: Gfap glial fibrillary acidic protein [ Mus musculus ]
• Official Symbol: GFAP
• Synonyms: GFAP; glial fibrillary acidic protein; intermediate filament protein; AI836096
• Gene ID: 14580
• mRNA Refseq: NM_001131020
• Protein Refseq: NP_001124492

Reviews

05/11/2022

Fast, efficient customer service.

12/12/2021

Product works great in assays.

07/16/2021

No problems, satisfied customer.

Q&As

What is the main function of GFAP in the central nervous system?

GFAP is crucial for maintaining the structure and function of astrocytes in the CNS.

How is GFAP used as a biomarker in neurological studies?

GFAP is used as a biomarker to assess astrocyte activation and neural damage.

How does GFAP contribute to the structure and support of astrocytes?

It forms intermediate filaments, providing mechanical support and stability to astrocytes.

What role does GFAP play in the response to brain injury?

It plays a protective role, participating in the glial scar formation post-injury.

How can dysregulation of GFAP affect neural function?

Dysregulation of GFAP can lead to impaired astrocyte function and neural dysfunction.

In which conditions is an increase in GFAP levels observed?

Increased GFAP levels are observed in gliosis, neurodegenerative diseases, and brain injuries.

Are there therapeutic interventions targeting GFAP for neurological disorders?

Therapeutic interventions may aim at modulating GFAP expression to mitigate neural damage.