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Recombinant Mouse Gp1ba protein, His & T7-tagged

Cat.No. : Gp1ba-1512M
Product Overview : Recombinant Mouse Gp1ba aa. (Gln17~Thr282 (Accession # O35930)) fused with N-terminal His & T7 tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Source : E. coli
Species : Mouse
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 33.3kDa.
Protein length : Gln17~Thr282 (Accession # O35930)
Endotoxin : <1.0EU per 1µg (determined by the LAL method).
Purity : >90%
Characteristic : The isoelectric point is 6.4.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Gp1ba glycoprotein 1b, alpha polypeptide [ Mus musculus (house mouse) ]
Official Symbol : Gp1ba
Synonyms : GPIba; GPIbalpha; GP-Ib alpha; glycoprotein Ibalpha; platelet glycoprotein Ib alpha chain
Gene ID : 14723
mRNA Refseq : NM_010326.2
Protein Refseq : NP_034456.2
UniProt ID : O35930

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the primary function of Glycoprotein Ib platelet subunit alpha (GP1BA) in platelet physiology and hemostasis? 05/05/2022

Glycoprotein Ib platelet subunit alpha (GP1BA) plays a crucial role in platelet physiology and hemostasis, specifically in platelet adhesion.

What diseases or conditions are associated with dysregulation or abnormal expression of GP1BA? 11/24/2021

Dysregulation or abnormal expression of GP1BA is associated with conditions such as Bernard-Soulier syndrome and other platelet disorders.

How does GP1BA contribute to platelet adhesion and the formation of platelet plugs at sites of vascular injury? 12/03/2020

GP1BA contributes to platelet adhesion by interacting with von Willebrand factor (vWF), facilitating platelet plug formation at vascular injury sites.

What are the interactions or binding partners of GP1BA, and how do they influence platelet function? 08/13/2020

Interactions or binding partners of GP1BA include vWF and other components of the platelet glycoprotein Ib-IX-V complex, influencing platelet function.

How does GP1BA participate in the regulation of blood clotting and coagulation cascades? 01/06/2019

GP1BA participates in the regulation of blood clotting and coagulation cascades by initiating platelet activation and aggregation.

In which cellular compartments is GP1BA predominantly localized, especially within platelets? 08/24/2018

GP1BA is predominantly localized on the surface of platelets, especially within the platelet membrane.

Are there therapeutic implications or potential targets related to GP1BA in diseases involving platelet disorders? 03/06/2018

There are potential therapeutic implications related to GP1BA in diseases involving platelet disorders, making it a target for drug development.

Customer Reviews (3)

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Reviews
11/04/2022

    Its compatibility with collaborative platforms and open-source tools facilitated sharing and reproducibility of our experiments.

    04/12/2022

      The product's support in the form of educational resources positively impacted the learning curve for our researchers.

      06/24/2016

        The product's track record of being featured in influential publications positively influenced our decision to use it.

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