Recombinant Mouse Gria1 Protein, MYC/DDK-tagged

• Cat.No.: Gria1-1062M
• Product Overview: Purified recombinant protein of full-length mouse glutamate receptor, ionotropic, AMPA1 (alpha 1) (Gria1), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
• Molecular Mass: 101.6 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) [ Mus musculus (house mouse) ]
• Official Symbol: Gria1
• Synonyms: Gria1; glutamate receptor, ionotropic, AMPA1 (alpha 1); Glr1; Glr-1; GluA1; GluRA; Glur1; HIPA1; GluR-A; Glur-1; gluR-K1; 2900051M01Rik; glutamate receptor 1; AMPA-selective glutamate receptor 1; glutamate receptor A; glutamate receptor ionotropic, AMPA 1
• Gene ID: 14799
• mRNA Refseq: NM_008165
• Protein Refseq: NP_032191
• UniProt ID: Q7TNB5