Recombinant Mouse Hc Protein Hc-071M

Recombinant Mouse Hc Protein

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Mouse Hc Protein

Recombinant Mouse Hc Protein

Hc Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : Hc-071M
Product Overview : Purified recombinant protein of Mouse hemolytic complement (Hc) without tag was expressed in E.coli.
Description : This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mice with a homozygous mutation in this gene exhibit impaired bone fracture healing and an enhanced inflammatory response in an allergic lung disease model.
Source : E. coli
Species : Mouse
Molecular Mass : 9 kDa
AA Sequence : MNLHLLRQKI EEQAAKYKHS VPKKCCYDGA RVNFYETCEE RVARVTIGPL CIRAFNECCT IANKIRKESP HKPVQLGR
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Purity : >95%, as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Storage : Store at -80 centigrade.
Storage Buffer : Lyophilized from a 0.2 µM filtered solution of 20mM PB, 350mM NaCl, pH 7.5
Reconstitution : Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Gene Name : Hc hemolytic complement [ Mus musculus (house mouse) ]
Official Symbol : Hc
Synonyms : Hc; hemolytic complement; C5; He; C5a; Hfib2; complement C5; hepatic fibrogenesis 2
Gene ID : 15139
mRNA Refseq : NM_010406
Protein Refseq : NP_034536
UniProt ID : A0A0J9YUU3

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy