Recombinant Mouse Hexa Protein, MYC/DDK-tagged


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Recombinant Mouse Hexa Protein, MYC/DDK-tagged

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Cat.No. : Hexa-1116M
Product Overview : Purified recombinant protein of full-length mouse hexosaminidase A (Hexa), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
Description : This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mice lacking the encoded protein exhibit accumulation of gangliosides in the brain and membranous cytoplasmic bodies in neurons. Certain mutations in the human ortholog of this gene cause Tay-Sachs disease.
Source : HEK293T
Species : Mouse
Molecular Mass : 60.6 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Hexa hexosaminidase A [ Mus musculus (house mouse) ]
Official Symbol : Hexa
Synonyms : Hexa; hexosaminidase A; Hex-1; beta-hexosaminidase subunit alpha; N-acetyl-beta-glucosaminidase subunit alpha; beta-N-acetylhexosaminidase subunit alpha; hexosaminidase subunit A; EC
Gene ID : 15211
mRNA Refseq : NM_010421
Protein Refseq : NP_034551
UniProt ID : P29416
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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