Recombinant Mouse Hhex Protein, MYC/DDK-tagged

• Cat.No.: Hhex-1124M
• Product Overview: Purified recombinant protein of full-length mouse hematopoietically was expressed homeobox (Hhex), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Recognizes the DNA sequence 5'-ATTAA-3' (PubMed:10804173). Transcriptional repressor (PubMed:10804173). Activator of WNT-mediated transcription in conjunction with CTNNB1 (PubMed:16936074). Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (PubMed:16936074). May play a role in hematopoietic differentiation (PubMed:8096636).
• Molecular Mass: 30 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hhex hematopoietically expressed homeobox [ Mus musculus (house mouse) ]
• Official Symbol: Hhex
• Synonyms: Hhex; hematopoietically expressed homeobox; Hex; Prh; Hex1; Prhx; Hhex-rs2; hematopoietically-expressed homeobox protein Hhex; hematopoietically expressed homeobox, related sequence 2; homeobox protein HEX; homeobox protein PRH; mHex
• Gene ID: 15242
• mRNA Refseq: NM_008245
• Protein Refseq: NP_032271
• UniProt ID: P43120