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Recombinant Mouse Hmox1 Protein, MYC/DDK-tagged

Cat.No. : Hmox1-1141M
Product Overview : Purified recombinant protein of full-length mouse heme oxygenase 1 (Hmox1), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
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Description : Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 33.4 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Hmox1 heme oxygenase 1 [ Mus musculus (house mouse) ]
Official Symbol : Hmox1
Synonyms : Hmox1; heme oxygenase 1; HO1; HO-1; Hmox; Hemox; Hsp32; D8Wsu38e; heme oxygenase 1; P32 protein; heme oxygenase (decycling) 1; hemoxygenase; EC 1.14.14.18
Gene ID : 15368
mRNA Refseq : NM_010442
Protein Refseq : NP_034572
UniProt ID : P14901

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can you discuss the role of HMOX1 in modulating the immune response in the context of infectious diseases, and how its induction may impact host-pathogen interactions? 03/02/2022

HMOX1 modulates the immune response during infectious diseases, influencing host-pathogen interactions. Its induction can contribute to an anti-inflammatory environment and impact the outcome of infections.

How does HMOX1 contribute to the regulation of iron homeostasis, and what are the molecular mechanisms involved in its interaction with iron-responsive elements? 06/10/2020

HMOX1 regulates iron homeostasis by releasing free iron during heme degradation. Its interaction with iron-responsive elements influences cellular iron levels and responses to iron availability.

What is the relationship between HMOX1 and oxidative stress-induced autophagy, and how does this connection influence cellular responses to stressors? 01/23/2019

HMOX1 is linked to oxidative stress-induced autophagy, contributing to cellular adaptation and survival. This connection influences the cellular response to stressors by promoting self-cleaning mechanisms.

Can you discuss the role of HMOX1 in vascular health and its impact on endothelial function, particularly in the context of cardiovascular diseases? 12/18/2018

HMOX1 plays a role in vascular health by protecting endothelial cells. Its anti-inflammatory and vasodilatory effects contribute to cardiovascular protection and may have implications for disease prevention.

How does HMOX1 participate in the modulation of the immune response, and what are the mechanisms by which it influences inflammatory pathways? 10/14/2018

HMOX1 modulates the immune response by suppressing inflammation. It inhibits pro-inflammatory pathways by influencing transcription factors and inhibiting the production of inflammatory mediators.

Customer Reviews (3)

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Reviews
10/03/2021

    A reliable source for top-notch proteins. Fast shipping is a big plus.

    04/14/2020

      Exceptional service! This product has become a staple in our lab.

      09/30/2018

        Impressed with the product's quality. Shipping is always on time.

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