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Recombinant Mouse Hopx Protein, Myc/DDK-tagged

Cat.No. : Hopx-3431M
Product Overview : Purified recombinant protein of mouse full-length HOP homeobox (Hopx), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
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Description : Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 8.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Hopx HOP homeobox [ Mus musculus (house mouse) ]
Official Symbol : Hopx
Synonyms : HOPX; HOP homeobox; homeodomain-only protein; mOB1; odd homeobox 1; homeobox only domain; homeobox-only protein; odd homeobox protein 1; homeodomain only protein; Hod; Hop; Ob1; Obl; Hdop; Toto; Cameo; AI848177; AW490897; 1110018K11Rik; 1200015P04Rik; 2300002F06Rik
Gene ID : 74318
mRNA Refseq : NM_001159901
Protein Refseq : NP_001153373
UniProt ID : Q8R1H0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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