Recombinant Mouse Igf2 Protein Igf2-1224M

Recombinant Mouse Igf2 Protein


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Recombinant Mouse Igf2 Protein

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Cat.No. : Igf2-1224M
Product Overview : Purified recombinant protein of Mouse insulin-like growth factor 2 (Igf2), transcript variant 2 (Ala25-Glu91) without tag was was expressed in E. coli.
Description : This gene encodes a member of the insulin-like growth factor (IGF) family of proteins that promote growth and development during fetal and postnatal life. It is an imprinted gene that is expressed only from the paternal allele. The encoded protein undergoes proteolytic processing to generate a mature peptide. The transgenic overexpression of this gene in mice results in prenatal overgrowth, polyhydramnios, fetal and neonatal lethality, disproportionate organ overgrowth including tongue enlargement, and skeletal abnormalities. Mice lacking the encoded protein exhibit growth deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.
Source : E. coli
Species : Mouse
Bio-activity : The ED50 is 10 - 30 ng/ml, corresponding to a specific activity of 0.3 - 1 x 10^5 units/mg, determined by the dose dependent stimulation of MCF-7 cell proliferation.
Molecular Mass : 7.4 kDa
Endotoxin : Less than 0.01 ng per µg protein as determined by the LAL method
Purity : >98%, as determined by Coomassie stained SDS-PAGE.
Stability : Unopened vial can be stored between 2 centigrade and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 centigrade and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Storage : Store at -80 centigrade.
Concentration : Protein formulated and vialed at >50 µg/mL in specified buffer
Storage Buffer : 1 x PBS
Gene Name : Igf2 insulin-like growth factor 2 [ Mus musculus (house mouse) ]
Official Symbol : Igf2
Synonyms : Igf2; insulin-like growth factor 2; Mpr; M6pr; Peg2; Igf-2; Igf-II; AL033362; insulin-like growth factor II; multiplication-stimulating polypeptide
Gene ID : 16002
mRNA Refseq : NM_001122736
Protein Refseq : NP_001116208
UniProt ID : P09535

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