Recombinant Mouse Il27ra Protein, Myc/DDK-tagged

• Cat.No.: Il27ra-3519M
• Product Overview: Purified recombinant protein of mouse full-length interleukin 27 receptor, alpha (Il27ra), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 69 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Il27ra interleukin 27 receptor, alpha [ Mus musculus (house mouse) ]
• Official Symbol: Il27ra
• Synonyms: Il27ra; interleukin 27 receptor, alpha; IL-; Tcc; CRL1; Tccr; WSX-; Wsx1; WSX-1; IL-27R; zcytor1; interleukin-27 receptor subunit alpha; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; IL-27RA; T cell cytokine receptor; T cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1; cytokine receptor family, class 1 (WSXWS), member 1; type I T-cell cytokine receptor
• Gene ID: 50931
• mRNA Refseq: NM_016671
• Protein Refseq: NP_057880
• UniProt ID: O70394

Reviews

03/19/2022

Good stability, stable structure, not easy to deteriorate.

12/08/2021

The preparation process is very convenient and suitable for novice operators.

02/21/2020

This method is highly sensitive and can detect small amounts of protein.

Q&As

What is the use of Il27ra?

In general, Il27ra should be administered by subcutaneous injection. For specific use, follow your doctor's advice and read the drug label carefully.

What is the action mechanism of Il27ra?

Il27ra regulates the function of immune cells by binding to its receptor, inhibiting inflammatory response and enhancing antiviral ability.

Does the clinical applications of Il27ra?

It is mainly used in clinical treatment of immune-related diseases, such as tumors, autoimmune diseases and so on.

Can Il27ra be used with other drugs?

It can be used in conjunction with other medications in certain cases, but be sure to inform your doctor about the medications you are using to avoid the possibility of drug interactions.

Can Il27ra be used in children?

The use of Il27ra in children is not yet clear, please follow the guidance of your doctor.

What are the side effects of Il27ra?

No significant side effects of recombinant Il27ra have been found, but common adverse reactions such as local reactions and anaphylaxis may occur.