Recombinant Mouse Il31ra Protein, Myc/DDK-tagged
Cat.No. : | Il31ra-3520M |
Product Overview : | Purified recombinant protein of mouse full-length interleukin 31 receptor A (cDNA clone MGC:76531 IMAGE:30475340), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 56.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Il31ra interleukin 31 receptor A [ Mus musculus (house mouse) ] |
Official Symbol : | Il31ra |
Synonyms : | Il31ra; interleukin 31 receptor A; G; GLM; GPL; CRL3; Glmr; NR10; GLM-R; interleukin-31 receptor subunit alpha; IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31R-alpha; IL-31RA; class I cytokine receptor; cytokine receptor NR10; gp130-like monocyte receptor; gp130-like receptor; interleukin 31RA; interleukin-31 receptor subunit alpha short peptide; mGLM-R; novel cytokine receptor 10; zcytoR17 |
Gene ID : | 218624 |
mRNA Refseq : | NM_139299 |
Protein Refseq : | NP_647460 |
UniProt ID : | Q8K5B1 |
Products Types
◆ Recombinant Protein | ||
IL31RA-4515M | Recombinant Mouse IL31RA Protein, His (Fc)-Avi-tagged | +Inquiry |
IL31RA-5191H | Recombinant Human IL31RA Protein, GST-tagged | +Inquiry |
IL31RA-2312H | Recombinant Human IL31RA Protein, His-tagged | +Inquiry |
IL31RA-1920H | Recombinant Human IL31RA Protein, MYC/DDK-tagged | +Inquiry |
IL31RA-1350H | Acitve Recombinant Human IL31RA protein(Met1-Ser516), hFc-tagged | +Inquiry |
◆ Lysates | ||
IL31RA-854HCL | Recombinant Human IL31RA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionRecombinant IL31RA is promising as a potential treatment for eczema, but further research and clinical trials are needed to confirm its efficacy.
The research of IL31RA is ongoing, and there are some relevant research results, but more experiments are needed to confirm its mechanism of action and clinical application.
IL31RA is associated with some chronic diseases, such as asthma and eczema, but the specific mechanism still needs to be further studied.
The IL31RA can be used in drug development, possibly in the treatment of allergic diseases, skin inflammation and pain.
The current research on the side effects of IL31RA is not perfect, but there may be local injection site reactions, mild allergic reactions and other situations.
This protein is involved in the regulation of immune response and may play an important regulatory role in allergic diseases.
Customer Reviews (3)
Write a reviewSensitivity and accuracy of the experiment were significantly improved by using this protein.
The synthesis process is efficient and reliable, reducing experimental time and cost.
Good stability and is suitable for long-term storage and use.
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