Recombinant Mouse IL3RA Protein, hIgG-His-tagged

Cat.No. : IL3RA-03M
Product Overview : Recombinant Mouse IL3RA Protein, fused to hIgG-His-tag, was expressed in Insect Cell.
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Description : Enables interleukin-3 binding activity and interleukin-3 receptor activity. Acts upstream of or within interleukin-3-mediated signaling pathway; monocyte differentiation; and regulation of cell growth. Located in membrane. Is expressed in several structures, including cardiovascular system mesenchyme; dorsal aorta; early conceptus; genitourinary system; and umbilical or vitelline vessel. Orthologous to human IL3RA (interleukin 3 receptor subunit alpha).
Source : Insect Cell
Species : Mouse
Tag : hIgG-His
Form : Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 30% glycerol.
Molecular Mass : 61.5 kDa
Protein length : 17-331aa
AA Sequence : SDLAAVREAP PTAVTTPIQN LHIDPAHYTL SWDPAPGADI TTGAFCRKGR DIFVWADPGL ARCSFQSLSL CHVTNFTVFL GKDRAVAGSI QFPPDDDGDH EAAAQDLRCW VHEGQLSCQW ERGPKATGDV HYRMFWRDVR LGPAHNRECP HYHSLDVNTA GPAPHGGHEG CTLDLDTVLG STPNSPDLVP QVTITVNGSG RAGPVPCMDN TVDLQRAEVL APPTLTVECN GSEAHARWVA RNRFHHGLLG YTLQVNQSSR SEPQEYNVSI PHFWVPNAGA ISFRVKSRSE VYPRKLSSWS EAWGLVCPPE VMPVK
Endotoxin : < 1 EU per 1ug of protein (determined by LAL method).
Purity : > 90%
Applications : SDS-PAGE
Notes : For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
Storage : Can be stored at 2 centigrade to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/ml
SDS-PAGE: 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Gene Name : Il3ra interleukin 3 receptor, alpha chain [ Mus musculus (house mouse) ]
Official Symbol : IL3RA
Synonyms : Interleukin-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha,nterleukin-3 receptor class II alpha chain; L3RA; CD123; hIL-3Ra; IL3R; IL3RAY; IL3RX; IL3RY; CDW123; SUT-1
Gene ID : 16188
mRNA Refseq : NM_008369
Protein Refseq : NP_032395
UniProt ID : P26952

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Can Il3ra be personalized? 08/01/2022

The feasibility of personalized therapy depends on the specific disease type and patient situation, and more research is needed to determine the application of personalized therapy to Il3ra.

Does Il3ra have clinical application prospects? What are the prospects? 05/19/2022

Il3ra has certain promise in clinical application, especially in the treatment of immune-related diseases.

What is the action mechanism of Il3ra? 04/24/2022

Regulates the proliferation and differentiation of immune cells by binding to its interacting cytokine IL-3, and plays a role in regulating the function of the immune system.

How is the clinical trial of Il3ra progressing? 09/16/2020

Clinical trials of recombinant Il3ra have been conducted in different disease areas. At present, some early trials show its potential in the treatment of certain diseases, but more research is needed to verify its efficacy and safety.

What is the specific effect of Il3ra on the immune system? 08/06/2019

The Il3ra can regulate the proliferation and differentiation of different types of immune cells in the immune system, thus affecting the function of the immune system.

Does Il3ra have side effects? 05/24/2019

Il3ra is generally well tolerated, but some minor side effects such as headache and nausea may occur. Serious side effects are rare.

Customer Reviews (3)

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07/24/2022

    In special environment, good stability.

    05/25/2022

      Good crystallization property and good effect.

      06/29/2021

        Has the expected biological activity, such as enzyme activity and receptor binding activity, and so on.

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