Recombinant Mouse Il5ra Protein, His-tagged

• Cat.No.: Il5ra-64M
• Product Overview: Recombinant mouse Il5ra, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Description: Il5ra, also known as interleukin-5 receptor subunit alpha, is known to regulate the development and function of eosinophils. This protein is a therapeutic target for hypereosinophilic diseases including allergic inflammations and asthma. Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells.
• Source: Insect cells
• Species: Mouse
• Tag: His tag
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 37.8kDa (330aa)40-57KDa (SDS–PAGE under reducing conditions.)
• AA Sequence: DLLNHKKFLL LPPVNFTIKA TGLAQVLLHW DPNPDQEQRH VDLEYHVKIN APQEDEYDTR KTESKCVTPL HEGFAASVRT ILKSSHTTLASSWVSAELKA PPGSPGTSVT NLTCTTHTVV SSHTHLRPYQ VSLRCTWLVG KDAPEDTQYF LYYRFGVLTE KCQEYSRDAL NRNTACWFPRTFINSKGFEQ LAVHINGSSK RAAIKPFDQL FSPLAIDQVN PPRNVTVEIE SNSLYIQWEK PLSAFPDHCF NYELKIYNTK NGHIQKEKLIANKFISKIDD VSTYSIQVRA AVSSPCRMPG RWGEWSQPIY VGKERKSLVE WHLEHHHHHH
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: Il5ra interleukin 5 receptor, alpha [ Mus musculus ]
• Official Symbol: Il5ra
• Synonyms: IL5RA; IL-5RA; IL-5R-alpha; Il5r; CD125; CDw125
• Gene ID: 16192
• mRNA Refseq: NM_008370
• Protein Refseq: NP_032396
• Pathway: Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; IL-5 Signaling Pathway, organism-specific biosystem; Immune System, organism-specific biosystem
• Function: cytokine receptor activity; receptor activity