Recombinant Mouse Il6ra, His tagged

Cat.No. : Il6ra-2297M
Product Overview : Recombinant Mouse Il6ra (NP_034689.2) extracellular domain (Ile 44-Glu 357), fused with a C-terminal polyhistidine tag, was produced in Human Cell.
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Source : HEK293
Species : Mouse
Tag : His
Form : Lyophilized from sterile 50 mM Tris, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant mouse IL6Rα comprises 349 amino acids with a predicted molecular mass of 39 kDa. As a result of glycosylation, it migrates as an approximately 55-60 kDa band in SDS-PAGE under reducing conditions.
Protein Length : Ile 44-Glu 357
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 97 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : Il6ra interleukin 6 receptor, alpha [ Mus musculus ]
Official Symbol : Il6ra
Synonyms : IL6RA; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; IL-6RA; IL-6R 1; IL-6R-alpha; IL-6R subunit alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; Il6r; CD126; IL-6R; MGC30256;
Gene ID : 16194
mRNA Refseq : NM_010559
Protein Refseq : NP_034689

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the pharmacological action of Il6ra? 07/10/2021

Il6ra blocks the binding of the interleukin-6 receptor by acting on it, thereby affecting its immunomodulatory effect and reducing inflammation.

Which diseases is Il6ra recombinant more effective in treating? 06/21/2021

The efficacy of Il6ra is related to the severity of the disease, disease type and individual differences of patients, and should be judged by professional physicians according to the situation.

What diseases can recombinant Il6ra be used to treat? 02/10/2020

Il6ra can be used to treat rheumatoid arthritis, psoriasis, alopecia areata and other autoimmune diseases.

Does Il6ra treat diseases with side effects? 08/14/2019

Almost all treatments have some kind of side effect, but the occurrence of side effects can be reduced with proper dosing and monitoring.

What is the mechanism of Il6ra? 08/08/2019

Recombinant Il6ra inhibits the immune response by inhibiting the cytokine activity of interleukin-6.

What are the clinical prospects of Il6ra? 03/25/2019

In addition to the autoimmune diseases mentioned above, Il6ra may also be used in the future to treat chronic inflammatory bowel disease, neurodegenerative diseases, and cancer.

Customer Reviews (3)

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12/08/2021

    It has good effect and stability in gene expression regulation.

    05/31/2020

      Will not interact with other drugs, will not affect.

      04/12/2019

        The application performance is stable in common colorimetric reactions.

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