Recombinant Mouse Il6ra protein, His-tagged

Cat.No. : Il6ra-583M
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Product overview : Recombinant Mouse Il6ra (Q3URV7) aa. (Ala52~Ala204) fused with His tag was produced in E. coli cells.
Source : E. coli
Species : Mouse
Tag : His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 18kDa; Accurate Molecular Mass: 18kDa as determined by SDS-PAGE reducing conditions.
Protein length : Ala52~Ala204
Purity : >98%
Characteristic : Isoelectric point is 6.5.
Applications : Cell culture; Activity Assays.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 0.05% sarcosyl and 5% trehalose.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex
Gene Name : Il6ra interleukin 6 receptor, alpha [ Mus musculus (house mouse) ]
Official Symbol : Il6ra
Synonyms : Il6ra; interleukin 6 receptor, alpha; Il6r; CD126; IL-6R; IL-6RA; IL-6R-alpha; interleukin-6 receptor subunit alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL-6R 1; IL-6R subunit alpha
Gene ID : 16194
mRNA Refseq : NM_001310676.1
Protein Refseq : NP_001297605.1
UniProt ID : Q3URV7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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Q&As (6)

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What is the pharmacological action of Il6ra? 07/10/2021

Il6ra blocks the binding of the interleukin-6 receptor by acting on it, thereby affecting its immunomodulatory effect and reducing inflammation.

Which diseases is Il6ra recombinant more effective in treating? 06/21/2021

The efficacy of Il6ra is related to the severity of the disease, disease type and individual differences of patients, and should be judged by professional physicians according to the situation.

What diseases can recombinant Il6ra be used to treat? 02/10/2020

Il6ra can be used to treat rheumatoid arthritis, psoriasis, alopecia areata and other autoimmune diseases.

Does Il6ra treat diseases with side effects? 08/14/2019

Almost all treatments have some kind of side effect, but the occurrence of side effects can be reduced with proper dosing and monitoring.

What is the mechanism of Il6ra? 08/08/2019

Recombinant Il6ra inhibits the immune response by inhibiting the cytokine activity of interleukin-6.

What are the clinical prospects of Il6ra? 03/25/2019

In addition to the autoimmune diseases mentioned above, Il6ra may also be used in the future to treat chronic inflammatory bowel disease, neurodegenerative diseases, and cancer.

Customer Reviews (3)

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    It has good effect and stability in gene expression regulation.


      Will not interact with other drugs, will not affect.


        The application performance is stable in common colorimetric reactions.

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