Recombinant Mouse IL6ST protein, Fc-tagged
Cat.No. : | IL6ST-353M |
Product Overview : | Recombinant Mouse IL6ST protein (Gln23-Glu617), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-6 receptor subunit beta (IL6ST) is also known as IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, Interleukin-6 signal transducer, Membrane glycoprotein 130 (gp130), CD130, Oncostatin-M receptor subunit alpha and Il6st,which is single-pass type I membrane protein. IL6ST/gp130/CD130 can be found in tissues such as brain, heart, thymus, spleen, kidney, lung and liver and found in all the cell lines tested except BaF-B03.The expression of IL-6ST/gp130 is not restricted to IL6-responsive cells. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. IL6ST/CD130 can bind to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduce the signal. IL6ST/GP130 does not bind IL6 and may have a role in embryonic development. |
Source : | HEK293 |
Species : | Mouse |
Tag : | human IgG1 Fc |
Form : | Lyophilized from 0.22 um filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 93.3 kDa. The protein migrates as 120-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | 595 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | IL6ST |
Official Symbol : | IL6ST |
Synonyms : | IL6ST; interleukin 6 signal transducer; interleukin-6 receptor subunit beta; IL-6RB; IL-6R-beta; IL-6R subunit beta; membrane glycoprotein 130; IL-6 receptor subunit beta; interleukin-6 signal transducer; oncostatin-M receptor subunit alpha; CD130; gp130; AA389424; BB405851; D13Ertd699e; 5133400A03Rik |
Gene ID : | 16195 |
mRNA Refseq : | NM_010560 |
Protein Refseq : | NP_034690 |
UniProt ID : | Q6PDI9 |
Products Types
◆ Recombinant Protein | ||
IL6ST-1380H | Acitve Recombinant Human IL6ST protein(Met1-Ile618), His&hFc-tagged | +Inquiry |
IL6ST-225H | Recombinant Human IL6ST Protein, His (Fc)-Avi-tagged | +Inquiry |
Il6st-275M | Recombinant Mouse Il6st Protein, Fc-tagged | +Inquiry |
IL6ST-5171H | Recombinant Human IL6ST Protein, GST-tagged | +Inquiry |
IL6ST-1531M | Active Recombinant Mouse IL6ST protein(Met1-Glu617), hFc-tagged | +Inquiry |
◆ Lysates | ||
IL6ST-001MCL | Recombinant Mouse IL6ST cell lysate | +Inquiry |
IL6ST-1882RCL | Recombinant Rat IL6ST cell lysate | +Inquiry |
IL6ST-946CCL | Recombinant Cynomolgus IL6ST cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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