Recombinant Mouse INPP4B Protein

• Cat.No.: INPP4B-8224M
• Product Overview: Recombinant Mouse INPP4B full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Inpp4b inositol polyphosphate-4-phosphatase, type II [ Mus musculus ]
• Official Symbol: INPP4B
• Gene ID: 234515
• mRNA Refseq: NM_001024617.2
• Protein Refseq: NP_001019788.1
• UniProt ID: Q6P1Y8

Reviews

05/24/2018

It's user-friendliness made it a favorite among team members, enhancing collaboration.

05/15/2016

Time-sensitive assays were notably improved by the swift effects of the product.

03/25/2016

The product's manufacturer went above and beyond to ensure our satisfaction, strengthening our trust in the brand.

Q&As

What is the impact of INPP4B on cell survival?

INPP4B modulates cell survival by antagonizing the PI3K-AKT/PKB signaling pathway.

Which phosphoinositides does INPP4B hydrolyze?

INPP4B hydrolyzes phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-trisphosphate.

In what cellular process does INPP4B play a role?

INPP4B plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles.

What signaling pathway does INPP4B antagonize?

INPP4B antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides.

What is the main function of INPP4B?

INPP4B catalyzes the hydrolysis of the 4-position phosphate of various phosphoinositides.

Why is the lipid phosphatase activity of INPP4B important?

The lipid phosphatase activity of INPP4B is critical for tumor suppressor function.

How does INPP4B modulate cell cycle progression?

INPP4B modulates cell cycle progression by dephosphorylating phosphoinositides and thereby affecting cell cycle progression.