Recombinant Mouse Ipo11 Protein, Myc/DDK-tagged
Cat.No. : | Ipo11-3564M |
Product Overview : | Purified recombinant protein of mouse full-length importin 11 (Ipo11), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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- Gene Information
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Description : | Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of RPL12, and of UBE2E3. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 112.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Ipo11 importin 11 [ Mus musculus (house mouse) ] |
Official Symbol : | Ipo11 |
Synonyms : | IPO11; importin 11; importin-11; imp11; ran-binding protein 11; Ranbp11; AI314624; AW555235; 1700081H05Rik; 2510001A17Rik; E330021B14Rik |
Gene ID : | 76582 |
mRNA Refseq : | NM_029665 |
Protein Refseq : | NP_083941 |
UniProt ID : | Q8K2V6 |
Products Types
◆ Recombinant Protein | ||
IPO11-2333H | Recombinant Human IPO11 Protein, His-tagged | +Inquiry |
IPO11-4579M | Recombinant Mouse IPO11 Protein, His (Fc)-Avi-tagged | +Inquiry |
IPO11-8261M | Recombinant Mouse IPO11 Protein | +Inquiry |
◆ Lysates | ||
IPO11-5183HCL | Recombinant Human IPO11 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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