Recombinant Mouse Irf5 Protein, Myc/DDK-tagged


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Recombinant Mouse Irf5 Protein, Myc/DDK-tagged

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Cat.No. : Irf5-3576M
Product Overview : Purified recombinant protein of mouse full-length interferon regulatory factor 5 (Irf5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Transcription factor that plays a critical role in innate immunity by activating expression of type I interferon (IFN) IFNA and INFB and inflammatory cytokines downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction downstream of the TLR-activated, MyD88-dependent pathway.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 56.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Irf5 interferon regulatory factor 5 [ Mus musculus (house mouse) ]
Official Symbol : Irf5
Synonyms : IRF5; interferon regulatory factor 5; IRF-5; interferon regulatory factor 5 bone marrow; mirf5; AW491843
Gene ID : 27056
mRNA Refseq : NM_012057
Protein Refseq : NP_036187
UniProt ID : P56477
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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