Recombinant Mouse Kdm4a Protein, Myc/DDK-tagged
Cat.No. : | Kdm4a-3681M |
Product Overview : | Purified recombinant protein of mouse full-length lysine (K)-specific demethylase 4A (Kdm4a), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 120.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Kdm4a lysine (K)-specific demethylase 4A [ Mus musculus (house mouse) ] |
Official Symbol : | Kdm4a |
Synonyms : | KDM4A; lysine (K)-specific demethylase 4A; lysine-specific demethylase 4A; jumonji domain containing 2A; jumonji domain-containing protein 2A; jmjC domain-containing histone demethylation protein 3A; Jmjd2; JHDM3A; Jmjd2a; mKIAA0677; D4Ertd222e; MGC28562 |
Gene ID : | 230674 |
mRNA Refseq : | NM_001161823 |
Protein Refseq : | NP_001155295 |
UniProt ID : | Q8BW72 |
Products Types
◆ Recombinant Protein | ||
KDM4A-0532H | Recombinant Human KDM4A Protein (M1-L359), His tagged | +Inquiry |
KDM4A-010H | Recombinant Human KDM4A Protein, Strep II-tagged | +Inquiry |
KDM4A-018H | Recombinant Human KDM4A Protein, His-tagged | +Inquiry |
KDM4A-1241H | Recombinant Human KDM4A Protein, His (Fc)-Avi-tagged | +Inquiry |
KDM4A-0531H | Recombinant Human KDM4A Protein (M1-L359), Tag Free | +Inquiry |
◆ Lysates | ||
KDM4A-4996HCL | Recombinant Human KDM4A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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