Recombinant Mouse Klhl13 Protein, Myc/DDK-tagged

• Cat.No.: Klhl13-3710M
• Product Overview: Purified recombinant protein of mouse full-length kelch-like 13 (Klhl13), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.
• Molecular Mass: 72.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Klhl13 kelch-like 13 [ Mus musculus (house mouse) ]
• Official Symbol: Klhl13
• Synonyms: KLHL13; kelch-like 13 (Drosophila); kelch-like protein 13; BTB and kelch domain containing 2; BTB and kelch domain-containing protein 2; Bklhd2; AI451128; mKIAA1309; 1200009K10Rik; D130072F20Rik
• Gene ID: 67455
• mRNA Refseq: NM_026167
• Protein Refseq: NP_080443
• UniProt ID: Q80TF4