Recombinant Mouse Leptin Receptor

• Cat.No.: Lepr-1766M

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Non
• Description: Leptin receptor, also known as LEPR, and CD295 (cluster of differentiation 295) is a single-transmembrane-domain receptor of the cytokine-receptor family. Leptin receptor exists in multiple forms with a common extracellular domain and a variable length cytoplasmatic portion. Leptin receptor may act as a negative regulator of Leptin activity and it may maintain a pool of available bioactive Leptin by binding and delaying its clearance from circulation. Leptin receptor is considered a physiological marker of primate fetal lung maturity.
• Molecular Weight: The predicted molecular weight of Recombinant Mouse Leptin R is Mr 120 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 150-170 kDa.
• State Of Matter: Lyophilized.
• Purity: >97% by SDS Page and analyzed by silver stain.
• Endotoxin: <0.1 ng per 1 µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: Lepr leptin receptor [ Mus musculus ]
• Synonyms: Lepr; leptin receptor; db; Obr; obl; Leprb; Modb1; LEPROT; OB-RGRP; diabetes; MGC105189; obese-like; OB receptor; OTTMUSP00000008795; leptin receptor gene-related protein
• Gene ID: 16847
• mRNA Refseq: NM_001122899
• Protein Refseq: NP_001116371
• UniProt ID: P48356
• Chromosome Location: 4 C6; 4 46.7 cM
• Pathway: Adipocytokine signaling pathway; Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Neuroactive ligand-receptor interaction
• Function: cytokine receptor activity; protein binding; receptor activity; transmembrane receptor activity