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Recombinant Mouse Loxl2 Protein, His-tagged

Cat.No. : Loxl2-274M
Product Overview : Recombinant Mouse Loxl2(Pro53~Val160) fused with His tag at N-terminal was expressed in E. coli.
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Source : E. coli
Species : Mouse
Tag : His
Form : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Molecular Mass : 13.3kDa
Protein length : Pro53~Val160
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : Loxl2 lysyl oxidase-like 2 [ Mus musculus ]
Official Symbol : Loxl2
Synonyms : LOXL2; lysyl oxidase-like 2; lysyl oxidase homolog 2; lysyl oxidase-like protein 2; 1110004B06Rik; 4930526G11Rik; 9430067E15Rik; MGC102220;
Gene ID : 94352
mRNA Refseq : NM_033325
Protein Refseq : NP_201582

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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In what ways does LOXL2 impact tissue elasticity, and how is this relevant in clinical applications? 06/14/2021

LOXL2 promotes the cross-linking of elastin fibers, affecting tissue elasticity. Understanding these mechanisms can have implications in diseases where tissue flexibility is crucial, such as in cardiovascular conditions.

How does LOXL2 influence wound healing, and can it be targeted for therapeutic interventions? 03/04/2021

LOXL2 is involved in tissue repair and wound healing by modulating the extracellular matrix. Targeting LOXL2 may offer therapeutic opportunities to enhance or control the wound healing process.

Are there diagnostic applications of LOXL2 in clinical settings? 05/03/2020

Elevated levels of LOXL2 have been associated with certain diseases. Measuring LOXL2 levels can potentially serve as a diagnostic marker for conditions such as liver fibrosis and certain cancers.

Are there ongoing clinical trials targeting LOXL2 for therapeutic purposes? 06/08/2019

Yes, several clinical trials are exploring the potential of LOXL2 inhibitors in treating fibrosis and cancer. These trials aim to validate the efficacy and safety of targeting LOXL2 in clinical settings.

How does LOXL2 contribute to the clinical understanding of fibrosis? 06/28/2017

LOXL2 is implicated in fibrosis as it plays a key role in collagen cross-linking, influencing tissue stiffness and architecture, making it a potential target for anti-fibrotic therapies.

Customer Reviews (3)

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06/20/2022

    This protein exhibits outstanding performance in ELISA, providing accurate and reliable results in detecting and quantifying specific antigens.

    01/16/2022

      Its high sensitivity ensures the detection of even low abundance targets, making it a valuable tool in immunoassays.

      03/23/2016

        Its stability and compatibility with electron microscopy techniques make it an excellent choice for studying protein structures at high resolution.

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