Recombinant Mouse Lpin1 Protein, Myc/DDK-tagged

• Cat.No.: Lpin1-3810M
• Product Overview: Purified recombinant protein of mouse full-length lipin 1 (Lpin1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis and therefore controls the metabolism of fatty acids at different levels. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 102.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Lpin1 lipin 1 [ Mus musculus (house mouse) ]
• Official Symbol: Lpin1
• Synonyms: LPIN1; lipin 1; phosphatidate phosphatase LPIN1; lipin-1; fatty liver dystrophy protein; fld; Lipin1; Kiaa0188; mKIAA0188; 4631420P06
• Gene ID: 14245
• mRNA Refseq: NM_015763
• Protein Refseq: NP_056578
• UniProt ID: Q91ZP3