Recombinant Mouse Mapk10 Protein, Myc/DDK-tagged

• Cat.No.: Mapk10-3938M
• Product Overview: Purified recombinant protein of mouse full-length mitogen-activated protein kinase 10 (Mapk10), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 48.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Mapk10 mitogen-activated protein kinase 10 [ Mus musculus (house mouse) ]
• Official Symbol: Mapk10
• Synonyms: MAPK10; mitogen-activated protein kinase 10; MAPK 10; MAP kinase 10; SAPK/Erk/kinase 2; MAP kinase p49 3F12; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; c-Jun N-terminal kinase 3; mitogen activated protein kinase 10; stress-activated protein kinase JNK3; JNK3; Serk2; JNK3B1; JNK3B2; p493F12; p54bSAPK; SAPK(beta); C230008H04Rik
• Gene ID: 26414
• mRNA Refseq: NM_009158
• Protein Refseq: NP_033184
• UniProt ID: Q80W82