Recombinant Mouse Mastl Protein, Myc/DDK-tagged
Cat.No. : | Mastl-3968M |
Product Overview : | Purified recombinant protein of mouse full-length microtubule associated serine/threonine kinase-like (Mastl), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 96.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Mastl microtubule associated serine/threonine kinase-like [ Mus musculus (house mouse) ] |
Official Symbol : | Mastl |
Synonyms : | MASTL; microtubule associated serine/threonine kinase-like; serine/threonine-protein kinase greatwall; microtubule-associated serine/threonine-protein kinase-like; GW; GWL; THC2; C88295; MAST-L; 2700091H24Rik; MGC117975 |
Gene ID : | 67121 |
mRNA Refseq : | NM_025979 |
Protein Refseq : | NP_080255 |
UniProt ID : | Q8C0P0 |
Products Types
◆ Recombinant Protein | ||
MASTL-5382M | Recombinant Mouse MASTL Protein, His (Fc)-Avi-tagged | +Inquiry |
MASTL-1035Z | Recombinant Zebrafish MASTL | +Inquiry |
MASTL-9582M | Recombinant Mouse MASTL Protein | +Inquiry |
MASTL-156H | Active Recombinant Human MASTL Protein, GST-tagged | +Inquiry |
MASTL-757H | Recombinant Human MASTL, His-tagged | +Inquiry |
◆ Lysates | ||
MASTL-4456HCL | Recombinant Human MASTL 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket