Recombinant Mouse Mb21d1 protein, His & T7-tagged Mb21d1-1625M

Recombinant Mouse Mb21d1 protein, His & T7-tagged

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Recombinant Mouse Mb21d1 protein, His & T7-tagged

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Cat.No. : Mb21d1-1625M
Product Overview : Recombinant Mouse Mb21d1 aa. (Glu211~Lys395 (Accession # Q8C6L5)) fused with N-terminal His & T7 tag was produced in E. coli cells.
Description : The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants.
Source : E. coli
Species : Mouse
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 24.9kDa
Protein length : Glu211~Lys395 (Accession # Q8C6L5)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Isoelectric Point : 9.4
SDS-PAGE :

Gene Name : Mb21d1 Mab-21 domain containing 1 [ Mus musculus (house mouse) ]
Official Symbol : Mb21d1
Synonyms : Mb21d1; Mab-21 domain containing 1; cGAS; E330016A19Rik; cyclic GMP-AMP synthase; 2'3'-cGAMP synthase; cGAMP synthase; mab-21 domain-containing protein 1
Gene ID : 214763
mRNA Refseq : NM_173386.5
Protein Refseq : NP_775562.2
UniProt ID : Q8C6L5

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