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Recombinant Mouse Mcm7 Protein, Myc/DDK-tagged

Cat.No. : Mcm7-3998M
Product Overview : Purified recombinant protein of mouse full-length minichromosome maintenance complex component 7 (Mcm7), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 81.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Mcm7 minichromosome maintenance complex component 7 [ Mus musculus (house mouse) ]
Official Symbol : Mcm7
Synonyms : MCM7; minichromosome maintenance deficient 7 (S. cerevisiae); DNA replication licensing factor MCM7; CDC47 homolog; mini chromosome maintenance deficient 7; Mcmd7; mCDC47; AI747533
Gene ID : 17220
mRNA Refseq : NM_008568
Protein Refseq : NP_032594
UniProt ID : Q61881

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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