Recombinant Mouse Memo1 Protein, Myc/DDK-tagged

• Cat.No.: Memo1-4031M
• Product Overview: Purified recombinant protein of mouse full-length mediator of cell motility 1 (Memo1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
• Molecular Mass: 33.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Memo1 mediator of cell motility 1 [ Mus musculus (house mouse) ]
• Official Symbol: Memo1
• Synonyms: Memo1; mediator of cell motility 1
• Gene ID: 76890
• mRNA Refseq: NM_133771
• Protein Refseq: NP_598532
• UniProt ID: Q91VH6