Recombinant Mouse Mocs3 Protein, Myc/DDK-tagged
Cat.No. : | Mocs3-4110M |
Product Overview : | Purified recombinant protein of mouse full-length molybdenum cofactor synthesis 3 (Mocs3), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 49.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Mocs3 molybdenum cofactor synthesis 3 [ Mus musculus (house mouse) ] |
Official Symbol : | Mocs3 |
Synonyms : | MOCS3; molybdenum cofactor synthesis 3; adenylyltransferase and sulfurtransferase MOCS3; MPT synthase sulfurylase; molybdopterin synthase sulfurylase; molybdenum cofactor synthesis protein 3; Uba4; 1700020H17Rik |
Gene ID : | 69372 |
mRNA Refseq : | NM_001160330 |
Protein Refseq : | NP_001153802 |
UniProt ID : | A2BDX3 |
Products Types
◆ Recombinant Protein | ||
MOCS3-5465H | Recombinant Human MOCS3 Protein, GST-tagged | +Inquiry |
MOCS3-5624M | Recombinant Mouse MOCS3 Protein, His (Fc)-Avi-tagged | +Inquiry |
MOCS3-143H | Recombinant Human MOCS3, His-tagged | +Inquiry |
MOCS3-10478Z | Recombinant Zebrafish MOCS3 | +Inquiry |
Mocs3-3194M | Recombinant Mouse Mocs3, His-tagged | +Inquiry |
◆ Lysates | ||
MOCS3-4259HCL | Recombinant Human MOCS3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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