Recombinant Mouse Mov10 Protein, Myc/DDK-tagged
Cat.No. : | Mov10-4121M |
Product Overview : | Purified recombinant protein of mouse full-length Mov10 RISC complex RNA helicase (Mov10), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Probable RNA helicase. Required for miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2. Restricts retrotransposition of long interspersed element-1 (LINE-1) in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1. Facilitates LINE-1 uridylation by TUT4 and TUT7. Required for embryonic viability and for normal central nervous system development and function. Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol. May function as a messenger ribonucleoprotein (mRNP) clearance factor. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 114 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Mov10 Mov10 RISC complex RNA helicase [ Mus musculus (house mouse) ] |
Official Symbol : | Mov10 |
Synonyms : | MOV10; Moloney leukemia virus 10; putative helicase MOV-10; moloney leukemia virus 10 protein; C77703; Mov-10 |
Gene ID : | 17454 |
mRNA Refseq : | NM_001163441 |
Protein Refseq : | NP_001156913 |
UniProt ID : | P23249 |
Products Types
◆ Recombinant Protein | ||
MOV10-2629R | Recombinant Rhesus Macaque MOV10 Protein, His (Fc)-Avi-tagged | +Inquiry |
MOV10-1424H | Recombinant Human MOV10 Protein, His (Fc)-Avi-tagged | +Inquiry |
MOV10-946H | Recombinant Human MOV10, GST-tagged | +Inquiry |
MOV10-2809R | Recombinant Rhesus monkey MOV10 Protein, His-tagged | +Inquiry |
MOV10-2067C | Recombinant Chicken MOV10 | +Inquiry |
◆ Lysates | ||
MOV10-4242HCL | Recombinant Human MOV10 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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