Recombinant Mouse Mpzl1 Protein, Myc/DDK-tagged

• Cat.No.: Mpzl1-4132M
• Product Overview: Purified recombinant protein of mouse full-length myelin protein zero-like 1 (Mpzl1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 2 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2, may be involved in regulation of integrin-mediated cell motility.
• Molecular Mass: 23 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Mpzl1 myelin protein zero-like 1 [ Mus musculus (house mouse) ]
• Official Symbol: Mpzl1
• Synonyms: MPZL1; myelin protein zero-like 1; myelin protein zero-like protein 1; protein zero-related; PZR; 1110007A10Rik
• Gene ID: 68481
• mRNA Refseq: NM_001001880
• Protein Refseq: NP_001001880
• UniProt ID: Q3TEW6