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Recombinant Mouse Msln Protein, Asp298-Ser600, C-His tagged, Biotinylated

Cat.No. : Msln-267M
Product Overview : Recombinant mouse MSLN/Mesothelin-C-His protein was developed from HEK293 and has a target region of C-His.
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Description : Predicted to be involved in cell-matrix adhesion. Predicted to act upstream of or within cell adhesion. Located in extracellular space. Is expressed in several structures, including body cavity or lining; genitourinary system; gut; heart; and respiratory system. Human ortholog(s) of this gene implicated in ovarian cancer; pancreas disease; pancreatic cancer; and pancreatic ductal carcinoma. Orthologous to human MSLN (mesothelin).
Source : HEK293
Species : Mouse
Tag : C-His
Protein length : Asp298-Ser600
Conjugation/Label : Biotin
Form : Lyophilised
Endotoxin : Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg).
Storage : The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade.
Storage Buffer : Lyophilised from 0.2 μm filtered PBS solution pH 7.4. Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20 sec, 5K RPM
Gene Name : Msln mesothelin [ Mus musculus ]
Official Symbol : Msln
Synonyms : MSLN; mesothelin; megakaryocyte potentiating factor; pre-pro-megakaryocyte-potentiating factor; MPF;
Gene ID : 56047
mRNA Refseq : NM_018857
Protein Refseq : NP_061345
UniProt ID : Q61468

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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Q&As (7)

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What is the primary role of MSLN in normal tissues? 12/07/2022

MSLN is normally expressed in mesothelial cells, playing a role in cell adhesion.

How is MSLN expression altered in cancerous cells? 03/19/2022

In cancer, MSLN expression is significantly upregulated.

In which types of cancer is MSLN overexpressed? 03/28/2021

MSLN is overexpressed in mesothelioma, ovarian, and pancreatic cancers.

Are there any therapeutic strategies targeting MSLN in cancer treatment? 02/25/2020

Therapies targeting MSLN include antibody-drug conjugates and CAR-T cell therapies.

How can MSLN levels be detected and measured in clinical settings? 10/07/2019

MSLN levels can be assessed through immunohistochemistry and serum biomarker tests.

What is the prognostic significance of MSLN overexpression in cancer patients? 11/23/2018

MSLN overexpression is often associated with poor prognosis in cancer patients.

How does MSLN contribute to cancer progression and metastasis? 11/07/2018

MSLN promotes tumor cell proliferation, invasion, and resistance to apoptosis.

Customer Reviews (3)

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    Very satisfied, great product.


      Product is high-quality.


        Excellent for experiments, reliable.

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