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Recombinant Mouse Mx1 Protein, Myc/DDK-tagged

Cat.No. : Mx1-4231M
Product Overview : Purified recombinant protein of mouse full-length MX dynamin-like GTPase 1 (Mx1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : This gene encodes a member of the Mx protein family of large GTPases, and functions in the innate immunity system. Interferon alpha/beta treatment or viral infection induces expression of this protein, which subsequently accumulates in the cytoplasm and inhibits viral replication. It has been shown to confer resistance to the influenza virus. This gene produces a functional protein in some feral mouse strains, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a deletion or a nonsense mutation that results in a non-functional gene product.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 72 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Mx1 MX dynamin-like GTPase 1 [ Mus musculus (house mouse) ]
Official Symbol : Mx1
Synonyms : MX1; myxovirus (influenza virus) resistance 1; interferon-induced GTP-binding protein Mx1; myxoma resistance protein 1; myxovirus (influenza) resistance 1 polypeptide; Mx; Mx-1; AI893580
Gene ID : 17857
mRNA Refseq : NM_010846
Protein Refseq : NP_034976
UniProt ID : P09922

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Where is the MX1 located? 07/13/2022

MX1 is localized in the nucleus.

What are the biological features of the MX1? 03/13/2022

MX1 has antiviral properties and can increase the resistance of animals to viruses.

In what tissues is MX1 primarily expressed? 10/29/2021

MX1 is predominantly expressed in the spleen and lungs.

MX1 is induced by what substances? 04/03/2021

Mx 1 protein is induced to be expressed by type I interferon, double-stranded RNA, or viral infection.

How is the p150Sal2 transcription factor related to MIX1? 03/14/2021

p150Sal2 promotes the expression of MX1 expression.

What is the structure domain of MX1? 02/19/2021

The highly conserved triple GTP-binding region at the N-terminus, the intermediate reaction region and a leucine zipper effector domain at the C-terminus.

Customer Reviews (3)

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Reviews
01/30/2023

    The MX1 proteins purchased from your company is suitable for ELISA.

    08/16/2022

      The technical expert will follow up on the progress of my experiments and provide constructive advice on the problems that arise in my experiments.

      07/21/2021

        Cheap price, high quality products, worth buying again.

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