Recombinant Mouse Necab3 Protein, Myc/DDK-tagged

• Cat.No.: Necab3-4353M
• Product Overview: Purified recombinant protein of mouse full-length N-terminal EF-hand calcium binding protein 3 (Necab3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 39.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Necab3 N-terminal EF-hand calcium binding protein 3 [ Mus musculus (house mouse) ]
• Official Symbol: Necab3
• Synonyms: NECAB3; N-terminal EF-hand calcium binding protein 3; N-terminal EF-hand calcium-binding protein 3; mXB51; X11L-binding protein 51; amyloid beta A4 protein-binding family A member 2-binding protein; amyloid beta (A4) precursor protein-binding family A member 1 binding protein; amyloid beta (A4) precursor protein-binding, family A, member 1 binding protein; amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein; Nip1; XB51; Apba2bp; AI853434; 2900010M17Rik
• Gene ID: 56846
• mRNA Refseq: NM_021546
• Protein Refseq: NP_067521
• UniProt ID: Q9D6J4