Recombinant Mouse Neu4 Protein, Myc/DDK-tagged
Cat.No. : | Neu4-4381M |
Product Overview : | Purified recombinant protein of mouse full-length sialidase 4 (Neu4), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides. Efficiently hydrolyzes gangliosides including alpha-(2->3)-sialylated GD1a and GM3 and alpha-(2->8)-sialylated GD3. Hydrolyzes poly-alpha-(2->8)-sialylated neural cell adhesion molecule NCAM1 likely at growth cones, suppressing neurite outgrowth in hippocampal neurons. May desialylate sialyl Lewis A and X antigens at the cell surface, down-regulating these glycan epitopes recognized by SELE/E selectin in the initiation of cell adhesion and extravasation. Has sialidase activity toward mucin, fetuin and sialyllactose. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 52.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Neu4 sialidase 4 [ Mus musculus (house mouse) ] |
Official Symbol : | Neu4 |
Synonyms : | NEU4; sialidase 4; sialidase-4; neuraminidase 4; N-acetyl-alpha-neuraminidase 4; 9330166I04 |
Gene ID : | 241159 |
mRNA Refseq : | NM_173772 |
Protein Refseq : | NP_776133 |
UniProt ID : | Q8BZL1 |
Products Types
◆ Recombinant Protein | ||
NEU4-1504H | Recombinant Human NEU4 Protein, His (Fc)-Avi-tagged | +Inquiry |
NEU4-6019M | Recombinant Mouse NEU4 Protein, His (Fc)-Avi-tagged | +Inquiry |
NEU4-4014H | Recombinant Human NEU4 Protein (Tyr22-Pro286), N-His tagged | +Inquiry |
NEU4-10593M | Recombinant Mouse NEU4 Protein | +Inquiry |
NEU4-301537H | Recombinant Human NEU4 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
NEU4-3869HCL | Recombinant Human NEU4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket