Recombinant Mouse Nkx3-1 Protein, Myc/DDK-tagged

• Cat.No.: Nkx3-1-4427M
• Product Overview: Purified recombinant protein of mouse full-length NK3 homeobox 1 (Nkx3-1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells. Plays a role in the formation of minor salivary glands (particularly palatine and lingual glands). Essential for appropriate differentiation and secretory function of the bulbourethral gland.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 26.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nkx3-1 NK3 homeobox 1 [ Mus musculus (house mouse) ]
• Official Symbol: Nkx3-1
• Synonyms: NKX3-1; NK-3 transcription factor, locus 1 (Drosophila); homeobox protein Nkx-3.1; homeobox protein NK-3 homolog A; Drosophila NK-3 transcription factor, locus 1; Bax; NKX3A; NKX3.1; Nkx-3.1; bagpipe
• Gene ID: 18095
• mRNA Refseq: NM_010921
• Protein Refseq: NP_035051
• UniProt ID: P97436