Recombinant Mouse NLRP3 Protein, His tagged
Cat.No. : | NLRP3-10722ME |
Product Overview : | Recombinant Mouse NLRP3 Protein with His-tag was expressed in E. coli. |
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Description : | Enables DNA-binding transcription factor binding activity and sequence-specific DNA binding activity. Involved in several processes, including positive regulation of T-helper cell differentiation; positive regulation of cytokine production; and response to bacterium. Acts upstream of or within several processes, including NLRP3 inflammasome complex assembly; activation of cysteine-type endopeptidase activity involved in apoptotic process; and defense response to virus. Located in cytoplasm and nucleus. Part of NLRP3 inflammasome complex. Is expressed in central nervous system and retina. Used to study CINCA Syndrome; familial cold autoinflammatory syndrome 1; and non-alcoholic fatty liver disease. Human ortholog(s) of this gene implicated in CINCA Syndrome; Muckle-Wells syndrome; autosomal dominant nonsyndromic deafness 34; familial cold autoinflammatory syndrome 1; and urticaria. Orthologous to human NLRP3 (NLR family pyrin domain containing 3). |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Molecular Mass : | The protein has a calculated MW of 36.17 kDa. |
AA Sequence : | MTSVRCKLAQYLEDLEDVDLKKFKM HLEDYPPEKGCIPVPRGQMEKADHL DLATLMIDFNGEEKAWAMAVWIFAA INRRDLWEKAKKDQPEWNDTCTSHS SMVCQEDSLEEEWMGLLGYLSRISI CKKKKDYCKMYRRHVRSRFYSIKDR NARLGESVDLNSRYTQLQLVKEHPS KQEREHELLTIGRTKMRDSPMSSLK LELLFEPEDGHSEPVHTVVFQGAAG IGKTILARKIMLDWALGKLFKDKFD YLFFIHCREVSLRTPRSLADLIVSC WPDPNPPVCKILRKPSRILFLMDGF DELQGAFDEH |
Gene Name : | Nlrp3 NLR family, pyrin domain containing 3 [ Mus musculus (house mouse) ] |
Official Symbol : | NLRP3 |
Synonyms : | NLRP3; NLR family, pyrin domain containing 3; NACHT, LRR and PYD domains-containing protein 3; cryopyrin; PYRIN-containing APAF1-like protein 1; cold autoinflammatory syndrome 1 homolog; mast cell maturation inducible protein 1; NACHT/LRR/pyrin domain-containing protein 3; cold autoinflammatory syndrome 1 protein homolog; mast cell maturation-associated-inducible protein 1; FCU; MWS; FCAS; Cias1; Mmig1; NALP3; Pypaf1; AII/AVP; AGTAVPRL; MGC129375 |
Gene ID : | 216799 |
mRNA Refseq : | NM_145827 |
Protein Refseq : | NP_665826 |
Products Types
◆ Recombinant Protein | ||
NLRP3-01H | Recombinant Human NLRP3 Protein, His/FLAG-tagged | +Inquiry |
NLRP3-02H | Recombinant Human NLRP3 Protein, Myc/DDK-tagged | +Inquiry |
NLRP3-01HE | Recombinant Human NLRP3 Protein, His-tagged | +Inquiry |
NLRP3-2866R | Recombinant Rhesus Macaque NLRP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
NLRP3-2493H | Recombinant Human NLRP3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
NLRP3-3799HCL | Recombinant Human NLRP3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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