"NOG" Related Products

Recombinant Mouse NOG Protein, Fc-tagged

Cat.No.: NOG-887M
Product Overview: Recombinant mouse NOG (P97466) (Met1-Cys232) was fused with the Fc region of human IgG1 at the C-terminus.
Source: HEK293
Species: Mouse
Tag: Fc
Predicted N Terminal: Gln 28
Form: Lyophilized from sterile 50 mM Tris, 100 mM Glycine, 10 mM NaCl, pH 7.5, 5%~8% trehalose and mannitol.
Bio-activity: Measured by its ability to inhibit BMP4 induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 0.06-0.3 μg/mL in the presence of 50 ng/mL of rhBMP4.
Molecular Mass: The recombinant mouse NOG/Fc comprises 454 amino acids and has a predicted molecular mass of 51 kDa.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: >90 % as determined by SDS-PAGE.
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name: Nog noggin [ Mus musculus ]
Official Symbol: NOG
Synonyms: NOG; noggin;
Gene ID: 18121
mRNA Refseq: NM_008711
Protein Refseq: NP_032737
MIM:
UniProt ID:
Pathway: ESC Pluripotency Pathways, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem; TGF Beta Signaling Pathway, organism-specific biosystem; TGF-beta signaling pathway, organism-specific
Function: cytokine binding; protein complex binding; protein homodimerization activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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