Recombinant Mouse Nova1 Protein, Myc/DDK-tagged

• Cat.No.: Nova1-4465M
• Product Overview: Purified recombinant protein of mouse full-length neuro-oncological ventral antigen 1 (Nova1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Functions to regulate alternative splicing in neurons by binding pre-mRNA in a sequence-specific manner to activate exon inclusion. It binds specifically to the sequence UCAUY. Most likely acts to activate the inclusion of exon E3A in the glycine receptor alpha-2 chain and of exon E9 in gamma-aminobutyric-acid receptor gamma-2 subunit via a distal downstream UCAU-rich intronic splicing enhancer.
• Molecular Mass: 51.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nova1 NOVA alternative splicing regulator 1 [ Mus musculus (house mouse) ]
• Official Symbol: Nova1
• Synonyms: NOVA1; neuro-oncological ventral antigen 1; RNA-binding protein Nova-1; ventral neuron-specific protein 1; Nova-1; G630039L02; 9430099M15Rik
• Gene ID: 664883
• mRNA Refseq: NM_021361
• Protein Refseq: NP_067336
• UniProt ID: Q9JKN6