Recombinant Mouse NRF1 Protein (1-503 aa), His-SUMO-tagged

• Cat.No.: NRF1-1800M
• Product Overview: Recombinant Mouse NRF1 Protein (1-503 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Full Length.

Specification

• Description: Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
• Source: E. coli
• Species: Mouse
• Tag: His-SUMO
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 69.6 kDa
• Protein length: 1-503 aa
• AA Sequence: MEEHGVTQTEHMATIEAHAVAQQVQ QVHVATYTEHSMLSADEDSPSSPED TSYDDSDILNSTAADEVTAHLAAAG PVGMAAAAAVATGKKRKRPHVFESN PSIRKRQQTRLLRKLRATLDEYTTR VGQQAIVLCISPSKPNPVFKVFGAA PLENVVRKYKSMILEDLESALAEHA PAPQEVNSELPPLTIDGIPVSVDKM TQAQLRAFIPEMLKYSTGRGKPGWG KESCKPIWWPEDIPWANVRSDVRTE EQKQRVSWTQALRTIVKNCYKQHGR EDLLYAFEDQQTQTQATTTHSIAHL VPSQTVVQTFSNPDGTVSLIQVGTG ATVATLADASELPTTVTVAQVNYSA VADGEVEQNWATLQGGEMTIQTTQA SEATQAVASLAEAAVAASQEMQQGA TVTMALNSEAAAHAVATLAEATLQG GGQIVLSGETAAAVGALTGVQDANG LVQIPVSMYQTVVTSLAQGNGPVQV AMAPVTTRISDSAVTMDGQAVEVVT LEQ
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: Nrf1 nuclear respiratory factor 1 [ Mus musculus ]
• Official Symbol: NRF1
• Synonyms: NRF1; nuclear respiratory factor 1; NRF-1; alpha-pal; C87038; D6Ertd415e
• Gene ID: 18181
• mRNA Refseq: NM_001164226
• Protein Refseq: NP_001157698
• UniProt ID: Q9WU00