Recombinant Mouse Pacsin3 Protein, Myc/DDK-tagged

• Cat.No.: Pacsin3-4650M
• Product Overview: Purified recombinant protein of mouse full-length protein kinase C and casein kinase substrate in neurons 3 (Pacsin3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 48.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pacsin3 protein kinase C and casein kinase substrate in neurons 3 [ Mus musculus (house mouse) ]
• Official Symbol: Pacsin3
• Synonyms: PACSIN3; protein kinase C and casein kinase substrate in neurons 3; protein kinase C and casein kinase II substrate protein 3; AW413130; 4921507A02Rik; 6330413E15Rik
• Gene ID: 80708
• mRNA Refseq: NM_028733
• Protein Refseq: NP_083009
• UniProt ID: Q99JB8